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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Dynein axonemal light chain 1

UniprotKB/SwissProt ID: Q4LDG9 (Q4LDG9)

Gene Name: DNAL1

Organism: Homo sapiens (Human)

Function: Part of the multisubunit axonemal ATPase complexes that generate the force for cilia motility and govern beat frequency (By similarity). Component of the outer arm dynein (ODA). May be involved in a mechanosensory feedback mechanism controlling ODA activity based on external conformational cues by tethering the outer arm dynein heavy chain (DNAH5) to the microtubule within the axoneme (By similarity). Important for ciliary function in the airways and for the function of the cilia that produce the nodal flow essential for the determination of the left-right asymmetry (PubMed:21496787)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton, cilium axoneme

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001611 Leu-rich_rpt
IPR025875 Leu-rich_rpt_4
IPR032675 LRR_dom_sf