Protein Name:
Nucleolar protein 56
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UniprotKB/SwissProt ID: Q4KLK7 (Q4KLK7)
Gene Name:
Nop56
Organism: Rattus norvegicus (Rat)
Function: Involved in the early to middle stages of 60S ribosomal subunit biogenesis. Required for the biogenesis of box C/D snoRNAs such U3, U8 and U14 snoRNAs. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) complexes that function in methylation of multiple sites on ribosomal RNAs (rRNAs) and messenger RNAs (mRNAs)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus, nucleolus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q4KLK7
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
142 |
LVKGLTDLSA C KAQLGLGHSY |
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| 2 |
211 |
VKIINDNATY C RLAQFIGNRR |
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| 3 |
384 |
NKCSIASRID C FSEVPTSVFG |
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| 4 |
570 |
FSEEPEAAAS C TKSSTKKKKK |
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