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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: NAD kinase 2, mitochondrial

UniprotKB/SwissProt ID: Q4G0N4 (Q4G0N4)

Gene Name: NADK2

Organism: Homo sapiens (Human)

Function: Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor. Also has weak NADH kinase activity in vitro; however NADH kinase activity is much weaker than the NAD(+) kinase activity and may not be relevant in vivo

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR017438 ATP-NAD_kinase_N
IPR017437 ATP-NAD_kinase_PpnK-typ_C
IPR016064 NAD/diacylglycerol_kinase_sf
IPR002504 NADK
IPR012355 NADK2_mit

The S-nitrosylation sites of Q4G0N4

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 193 TDPERSEGHL C LPVRYTHSFP  CCCCHHCHHH H HHHEECCHHH 
2 311 EKQKSSGLNL C TGTGSKAWSF  CCCCHHCHHH H HHHEECCHHH 
3 393 NRVFSSSRQR C FSSKVCVRSR  CCCCHHCHHH H HHHEECCHHH  19483679
4 58 GQGQPRELAG C GSRADGGFRP  CCCCHHCHHH H HHHEECCHHH