UniprotKB/SwissProt ID: Q42601 (Q42601)
Gene Name:
CARB
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Large subunit of the arginine-specific carbamoyl phosphate synthase (CPSase). CPSase catalyzes the formation of carbamoyl phosphate from the ammonia moiety of glutamine, hydrogencarbonate, and phosphate donated by ATP, constituting the first step of 2 biosynthetic pathways, one leading to arginine and/or urea and the other to pyrimidine nucleotides. The large subunit (synthetase) binds the substrates ammonia (free or transferred from glutamine from the small subunit), hydrogencarbonate and ATP and carries out an ATP-coupled ligase reaction, activating hydrogencarbonate by forming carboxy phosphate which reacts with ammonia to form carbamoyl phosphate. Required for mesophyll development
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Plastid, chloroplast
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