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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Thrombospondin type-1 domain-containing protein 4

UniprotKB/SwissProt ID: Q3UTY6 (Q3UTY6)

Gene Name: Thsd4

Organism: Mus musculus (Mouse)

Function: Promotes FBN1 matrix assembly. Attenuates TGFB signaling, possibly by accelerating the sequestration of large latent complexes of TGFB or active TGFB by FBN1 microfibril assembly, thereby negatively regulating the expression of TGFB regulatory targets, such as POSTN

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Secreted, extracellular space, extracellular matrix. Secreted. Secreted, extracellular space, extracellular matrix

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR050439 ADAMTS_ADAMTS-like
IPR045371 ADAMTS_CR_3
IPR010294 ADAMTS_spacer1
IPR010909 PLAC
IPR000884 TSP1_rpt
IPR036383 TSP1_rpt_sf