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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

UniprotKB/SwissProt ID: Q3ULD5 (Q3ULD5)

Gene Name: Mccc2

Organism: Mus musculus (Mouse)

Function: Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion matrix

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR034733 AcCoA_carboxyl_beta
IPR029045 ClpP/crotonase-like_dom_sf
IPR011763 COA_CT_C
IPR011762 COA_CT_N
IPR045190 MCCB/AccD1-like

The S-nitrosylation sites of Q3ULD5

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 131 TGIGRVSGVE C MIVANDATVK  CCHHHHHHHH H HHHCCCCCCH  1.78% 21278135
2 167 QEIALQNRLP C IYLVDSGGAN  CCHHHHHHHH H HHHCCCCCCH  3.65% 21278135
3 267 AEDLGGADLH C RKSGVTDHYA  CCHHHHHHHH H HHHCCCCCCH  8.34% 22178444
21278135
4 431 DGAKMVAAVA C AKVPKITVII  CCHHHHHHHH H HHHCCCCCCH  2.79% 21278135