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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Putative methyltransferase C9orf114 homolog

UniprotKB/SwissProt ID: Q3UHX9 (Q3UHX9)

Gene Name: Spout1

Organism: Mus musculus (Mouse)

Function: Required for association of the centrosomes with the poles of the bipolar mitotic spindle during metaphase. Also involved in chromosome alignment. May promote centrosome maturation probably by recruiting A-kinase anchor protein AKAP9 to centrosomes in early mitosis. Binds specifically to miRNA MIR145 hairpin, regulates MIR145 expression at a postranscriptional level (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR029028 Alpha/beta_knot_MTases
IPR012340 NA-bd_OB-fold
IPR003750 Put_MeTrfase
IPR029026 tRNA_m1G_MTases_N

The S-nitrosylation sites of Q3UHX9

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 140 FRGVGKKGQA C VQLARILQYL  CCCCCCCCCC C CCCCCHHHHH  1.22% 21278135