Protein Name:
Extended synaptotagmin-1
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UniprotKB/SwissProt ID: Q3U7R1 (Q3U7R1)
Gene Name:
Esyt1
Organism: Mus musculus (Mouse)
Function: Binds calcium (via the C2 domains) and translocates to sites of contact between the endoplasmic reticulum and the cell membrane in response to increased cytosolic calcium levels. Helps tether the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Acts as an inhibitor of ADGRD1 G-protein-coupled receptor activity in absence of cytosolic calcium (By similarity). Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endoplasmic reticulum membrane. Cell membrane
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Graphical Visualization of S-nitrosylation Sites:
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