Protein Name:
Extended synaptotagmin-2
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UniprotKB/SwissProt ID: Q3TZZ7 (Q3TZZ7)
Gene Name:
Esyt2
Organism: Mus musculus (Mouse)
Function: Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport. Plays a role in FGF signaling via its role in the rapid internalization of FGFR1 that has been activated by FGF1 binding; this occurs most likely via the AP-2 complex (By similarity). Promotes the localization of SACM1L at endoplasmic reticulum-plasma membrane contact sites (EPCS) (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane. Endoplasmic reticulum membrane
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Graphical Visualization of S-nitrosylation Sites:
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