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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: 26S proteasome non-ATPase regulatory subunit 1

UniprotKB/SwissProt ID: Q3TXS7 (Q3TXS7)

Gene Name: Psmd1

Organism: Mus musculus (Mouse)

Function: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR016642 26S_Psome_Rpn2
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR002015 Proteasome/cyclosome_rpt
IPR048570 PSMD1_RPN2_N
IPR040623 RPN2_C

The S-nitrosylation sites of Q3TXS7

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 633 GFILFRTPEQ C PSVVSLLSES  CCCCHHHHHH H CCCCCHHHHH  2.3%
2 659 RYGAAMALGI C CAGTGNKEAI  CCCCHHHHHH H CCCCCHHHHH  0.93%
3 898 QLKVLSMTET C RYQPFKPLSI  CCCCHHHHHH H CCCCCHHHHH  2.88% 21278135