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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Hexokinase-3

UniprotKB/SwissProt ID: Q3TRM8 (Q3TRM8)

Gene Name: Hk3

Organism: Mus musculus (Mouse)

Function: Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D-fructose 6-phosphate, respectively). Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6-phosphate

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR043129 ATPase_NBD
IPR001312 Hexokinase
IPR019807 Hexokinase_BS
IPR022673 Hexokinase_C
IPR022672 Hexokinase_N

The S-nitrosylation sites of Q3TRM8

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 18 GLHPGERASV C PHEGVPRPSG   
2 188 TLISWTKGFR C SGVEGQDVVQ   
3 839 QAVSRRAAQL C GAGVAAVVEK   
4 891 SATVRKLAPQ C TVTFLQSEDG   
5 914 KGAALVTAVA C RLTQMAHV--