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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Endoplasmic reticulum resident protein 44

UniprotKB/SwissProt ID: Q3T0L2 (Q3T0L2)

Gene Name: ERP44

Organism: Bos taurus (Bovine)

Function: Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1A and ERO1B in the endoplasmic reticulum

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Endoplasmic reticulum lumen

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR052643 ERP44
IPR041862 ERp44_PDI_b
IPR041870 ERp44_PDI_b
IPR036249 Thioredoxin-like_sf
IPR013766 Thioredoxin_domain

The S-nitrosylation sites of Q3T0L2

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 92 ANQVVFARVD C DQHSDIAQRY