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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Actin-depolymerizing factor 1

UniprotKB/SwissProt ID: Q39250 (Q39250)

Gene Name: ADF1

Organism: Arabidopsis thaliana (Mouse-ear cress)

Function: Actin-depolymerizing protein. Stimulates F-actin depolymerization. Involved in plant development, cell organ expansion and flowering by controlling breakdown of thick actin cables (PubMed:11402164). Severs actin filaments or bundles and promotes actin cytoskeleton disassembly (PubMed:21570971). Binds monomeric actin (G-actin) with a marked preference for the ADP-loaded form and inhibits the rate of nucleotide exchange on G-actin (PubMed:17538023)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR002108 ADF-H
IPR029006 ADF-H/Gelsolin-like_dom_sf
IPR017904 ADF/Cofilin

The S-nitrosylation sites of Q39250

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 80 YDFDFVTAEN C QKSKIFFIAW