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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Rac-like GTP-binding protein ARAC3

UniprotKB/SwissProt ID: Q38912 (Q38912)

Gene Name: ARAC3

Organism: Arabidopsis thaliana (Mouse-ear cress)

Function: Inactive GDP-bound Rho GTPases reside in the cytosol, are found in a complex with Rho GDP-dissociation inhibitors (Rho GDIs), and are released from the GDI protein in order to translocate to membranes upon activation. Involved in cell polarity control during the actin-dependent tip growth of root hairs, thus regulating root hair length and root hair initiation (PubMed:11387211, PubMed:30770391). Contributes, in a SPK1-dependent manner, to the prevention of cortical microtubules organization into parallel arrays oriented perpendicular to the axis of cell elongation to limit anisotropic cell growth during petal development (PubMed:31623377). SPK1-dependent activation is required for auxin-mediated inhibition of PIN2 internalization during gravitropic responses (PubMed:22683260)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Cell membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd
IPR001806 Small_GTPase
IPR003578 Small_GTPase_Rho