Protein Name:
Thiamine thiazole synthase, chloroplastic
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UniprotKB/SwissProt ID: Q38814 (Q38814)
Gene Name:
THI1
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance. Acts as a positive regulator for the abscisic acid-induced activation of slow type anion channels during stomatal closure by repressing CPK33 kinase activity
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Plastid, chloroplast. Mitochondrion. Cell membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q38814
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
216 |
LVAQNHHTQS C MDPNVMEAKI |
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| 2 |
231 |
VMEAKIVVSS C GHDGPFGATG |
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