UniprotKB/SwissProt ID: Q33DR3 (Q33DR3)
Gene Name:
Pdss2
Organism: Mus musculus (Mouse)
Function: Heterotetrameric enzyme that catalyzes the condensation of farnesyl diphosphate (FPP), which acts as a primer, and isopentenyl diphosphate (IPP) to produce prenyl diphosphates of varying chain lengths and participates in the determination of the side chain of ubiquinone (PubMed:16262699). Supplies nona and decaprenyl diphosphate, the precursors for the side chain of the isoprenoid quinones ubiquinone-9 (Q9) and ubiquinone-10 (Q10) respectively (PubMed:16262699). The enzyme adds isopentenyl diphosphate molecules sequentially to farnesyl diphosphate with trans stereochemistry (PubMed:16262699). May play a role during cerebellar development (PubMed:21871565). May regulate mitochondrial respiratory chain function (PubMed:18437205)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion
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