Protein Name:
tRNA (guanine(37)-N(1))-methyltransferase
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UniprotKB/SwissProt ID: Q32P41 (Q32P41)
Gene Name:
TRMT5
Organism: Homo sapiens (Human)
Function: Involved in mitochondrial tRNA methylation (PubMed:26189817). Specifically methylates the N1 position of guanosine-37 in various tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion matrix. Nucleus. Cytoplasm
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Graphical Visualization of S-nitrosylation Sites:
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