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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Prolyl 3-hydroxylase 1

UniprotKB/SwissProt ID: Q32P28 (Q32P28)

Gene Name: P3H1

Organism: Homo sapiens (Human)

Function: Basement membrane-associated chondroitin sulfate proteoglycan (CSPG). Has prolyl 3-hydroxylase activity catalyzing the post-translational formation of 3-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens, especially types IV and V. May be involved in the secretory pathway of cells. Has growth suppressive activity in fibroblasts

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Endoplasmic reticulum. Secreted, extracellular space, extracellular matrix

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR056585 Leprecan_dom
IPR005123 Oxoglu/Fe-dep_dioxygenase_dom
IPR039575 P3H
IPR006620 Pro_4_hyd_alph
IPR044862 Pro_4_hyd_alph_FE2OG_OXY
IPR011990 TPR-like_helical_dom_sf

The S-nitrosylation sites of Q32P28

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 645 KTVTAEVQPQ C GRAVGFSSGT