Protein Name:
Sprouty-related, EVH1 domain-containing protein 3
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UniprotKB/SwissProt ID: Q2MJR0 (Q2MJR0)
Gene Name:
SPRED3
Organism: Homo sapiens (Human)
Function: Tyrosine kinase substrate that inhibits growth-factor-mediated activation of MAP kinase (By similarity). Inhibits fibroblast growth factor (FGF)-induced retinal lens fiber differentiation, probably by inhibiting FGF-mediated phosphorylation of ERK1/2 (By similarity). Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane
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Graphical Visualization of S-nitrosylation Sites:
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