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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: WASH complex subunit 4

UniprotKB/SwissProt ID: Q2M389 (Q2M389)

Gene Name: WASHC4

Organism: Homo sapiens (Human)

Function: Acts as a component of the WASH core complex that functions as a nucleation-promoting factor (NPF) at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Early endosome

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR028191 WASH-4_N
IPR028283 WASH-7_C
IPR028282 WASH-7_central
IPR027307 WASH7

The S-nitrosylation sites of Q2M389

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 344 KKFYKSLLDI C KKVPAITLTA