Protein Name:
Protein CLEC16A
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UniprotKB/SwissProt ID: Q2KHT3 (Q2KHT3)
Gene Name:
CLEC16A
Organism: Homo sapiens (Human)
Function: Regulator of mitophagy through the upstream regulation of the RNF41/NRDP1-PRKN pathway. Mitophagy is a selective form of autophagy necessary for mitochondrial quality control. The RNF41/NRDP1-PRKN pathway regulates autophagosome-lysosome fusion during late mitophagy. May protect RNF41/NRDP1 from proteasomal degradation, RNF41/NRDP1 which regulates proteasomal degradation of PRKN. Plays a key role in beta cells functions by regulating mitophagy/autophagy and mitochondrial health
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endosome membrane. Lysosome membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q2KHT3
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
801 |
ATFIFSDHIR C IIAKQRLAKG |
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