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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Glutamine and serine-rich protein 1

UniprotKB/SwissProt ID: Q2KHR3 (Q2KHR3)

Gene Name: QSER1

Organism: Homo sapiens (Human)

Function: Plays an essential role in the protection and maintenance of transcriptional and developmental programs. Protects many bivalent promoters and poised enhancers from hypermethylation, showing a marked preference for these regulatory elements over other types of promoters or enhancers. Mechanistically, cooperates with TET1 and binds to DNA in a common complex to inhibit the binding of DNMT3A/3B and therefore de novo methylation

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Chromosome

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR052466 DNA_MethProtect_Complex
IPR025451 DUF4211

The S-nitrosylation sites of Q2KHR3

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 283 YPPSTTKIKS C STEQPLTSTK