UniprotKB/SwissProt ID: Q27433 (Q27433)
Gene Name:
mec-2
Organism: Caenorhabditis elegans
Function: Subunit of an amiloride-sensitive cation channel (degenerin channel complex) permeable for sodium, potassium, lithium and N-methylglucamine, and required for mechanosensory transduction (touch sensitivity) (PubMed:12478294). Positively regulates the activity of the putative mechanosensory transduction channel. May link the mechanosensory channel and the microtubule cytoskeleton of the touch receptor neurons. Required for the function of a set of six touch receptor neurons
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Membrane
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