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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Guanine nucleotide-binding protein alpha-17 subunit

UniprotKB/SwissProt ID: Q18434 (Q18434)

Gene Name: odr-3

Organism: Caenorhabditis elegans

Function: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems (PubMed:10192394). This specific G-alpha subunit plays an important role in olfaction and in cilia morphogenesis (PubMed:15342507, PubMed:9459442). Involved in chemotactic responses to attractants diacetyl, pyrazine, 2,4,5-trimethylthiazole, benzaldehyde, isoamyl alcohol, butanone and 2,3-pentanedione (PubMed:12694294). Displays a redundant function with gpa-3 in chemotactic responses (PubMed:12694294). Plays a role in the avoidance response to the noxious chemical quinine in ASH sensory neurons (PubMed:14988722). Involved in avoidance responses to copper, sodium dodecyl sulfate and linoleic acid (PubMed:12694294). Involved in osmotic avoidance and mechanosensory responses (PubMed:12694294). Involved in specifying fan-like morphology of cilia of head sensory neurons AWC (PubMed:9459442). Plays a role in the detection of preferred food sources by mediating the recognition of food odors in olfactory sensory neurons (PubMed:25009271)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell projection, cilium. Cell projection, dendrite

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001408 Gprotein_alpha_I
IPR001019 Gprotein_alpha_su
IPR011025 GproteinA_insert
IPR027417 P-loop_NTPase