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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Thiosulfate sulfurtransferase

UniprotKB/SwissProt ID: Q16762 (Q16762)

Gene Name: TST

Organism: Homo sapiens (Human)

Function: Formation of iron-sulfur complexes, cyanide detoxification or modification of sulfur-containing enzymes. Other thiol compounds, besides cyanide, can act as sulfur ion acceptors. Also has weak mercaptopyruvate sulfurtransferase (MST) activity (By similarity). Together with MRPL18, acts as a mitochondrial import factor for the cytosolic 5S rRNA. Only the nascent unfolded cytoplasmic form is able to bind to the 5S rRNA

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion matrix

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001763 Rhodanese-like_dom
IPR036873 Rhodanese-like_dom_sf
IPR001307 Thiosulphate_STrfase_CS
IPR045078 TST/MPST-like

The S-nitrosylation sites of Q16762

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 248 VDLSQPLIAT C RKGVTACHVA  CHHHHHHHHH H CHHHHHHHHH  2.9% 24105792
25040305
2 64 PGASFFDIEE C RDTASPYEMM  CHHHHHHHHH H CHHHHHHHHH  2.86%