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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Kynureninase

UniprotKB/SwissProt ID: Q16719 (Q16719)

Gene Name: KYNU

Organism: Homo sapiens (Human)

Function: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytosol

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR010111 Kynureninase
IPR015424 PyrdxlP-dep_Trfase
IPR015421 PyrdxlP-dep_Trfase_major
IPR015422 PyrdxlP-dep_Trfase_small

The S-nitrosylation sites of Q16719

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 327 DNKLQLIPGV C GFRISNPPIL   
2 425 FQELEKRGVV C DKRNPNGIRV   
3 45 EEDKLRHFRE C FYIPKIQDLP