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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Drebrin

UniprotKB/SwissProt ID: Q16643 (Q16643)

Gene Name: DBN1

Organism: Homo sapiens (Human)

Function: Actin cytoskeleton-organizing protein that plays a role in the formation of cell projections (PubMed:20215400). Required for actin polymerization at immunological synapses (IS) and for the recruitment of the chemokine receptor CXCR4 to IS (PubMed:20215400). Plays a role in dendritic spine morphogenesis and organization, including the localization of the dopamine receptor DRD1 to the dendritic spines (By similarity). Involved in memory-related synaptic plasticity in the hippocampus (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Cell projection, dendrite. Cytoplasm, cell cortex. Cell junction. Cell projection, growth cone

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR002108 ADF-H
IPR029006 ADF-H/Gelsolin-like_dom_sf

The S-nitrosylation sites of Q16643

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 613 EEEFAQSEEL C AKAPPPVFYN  CCCCCCCHHH H HHHHHHHHHH  4.06%
2 632 YNKPPEIDIT C WDADPVPEEE  CCCCCCCHHH H HHHHHHHHHH  2.94%
3 68 FENQKVMYGF C SVKDSQAALP  CCCCCCCHHH H HHHHHHHHHH  3.87%
4 96 VGEDVPDARK C ACASHVAKVA  CCCCCCCHHH H HHHHHHHHHH  2.91% 2212679