Protein Name:
Drebrin
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UniprotKB/SwissProt ID: Q16643 (Q16643)
Gene Name:
DBN1
Organism: Homo sapiens (Human)
Function: Actin cytoskeleton-organizing protein that plays a role in the formation of cell projections (PubMed:20215400). Required for actin polymerization at immunological synapses (IS) and for the recruitment of the chemokine receptor CXCR4 to IS (PubMed:20215400). Plays a role in dendritic spine morphogenesis and organization, including the localization of the dopamine receptor DRD1 to the dendritic spines (By similarity). Involved in memory-related synaptic plasticity in the hippocampus (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Cell projection, dendrite. Cytoplasm, cell cortex. Cell junction. Cell projection, growth cone
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q16643
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
613 |
EEEFAQSEEL C AKAPPPVFYN |
CCCCCCCHHH H HHHHHHHHHH |
4.06% |
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| 2 |
632 |
YNKPPEIDIT C WDADPVPEEE |
CCCCCCCHHH H HHHHHHHHHH |
2.94% |
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| 3 |
68 |
FENQKVMYGF C SVKDSQAALP |
CCCCCCCHHH H HHHHHHHHHH |
3.87% |
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| 4 |
96 |
VGEDVPDARK C ACASHVAKVA |
CCCCCCCHHH H HHHHHHHHHH |
2.91% |
2212679
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