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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Serine/arginine-rich splicing factor 7

UniprotKB/SwissProt ID: Q16629 (Q16629)

Gene Name: SRSF7

Organism: Homo sapiens (Human)

Function: Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1 RNA-binding activity. RNA-binding is semi-sequence specific

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus. Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
IPR034651 SRSF7_RRM
IPR001878 Znf_CCHC
IPR036875 Znf_CCHC_sf

The S-nitrosylation sites of Q16629

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 106 ARRPFDPNDR C YECGEKGHYA   
2 119 CGEKGHYAYD C HRYSRRRRSR   
3 73 AVRGLDGKVI C GSRVRVELST