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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Dihydropyrimidinase-related protein 2

UniprotKB/SwissProt ID: Q16555 (Q16555)

Gene Name: DPYSL2

Organism: Homo sapiens (Human)

Function: Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR006680 Amidohydro-rel
IPR011778 Hydantoinase/dihydroPyrase
IPR011059 Metal-dep_hydrolase_composite
IPR032466 Metal_Hydrolase
IPR050378 Metallo-dep_Hydrolases_sf

The S-nitrosylation sites of Q16555

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 132 QWREWADSKS C CDYSLHVDIS  CCCCCCCCCC C CCCCCEEEEC  2.05%
2 133 WREWADSKSC C DYSLHVDISE  CCCCCCCCCC C CCCCCEEEEC  7.7%
3 179 AFKDRFQLTD C QIYEVLSVIR  CCCCCCCCCC C CCCCCEEEEC  1.92%
4 248 RAITIANQTN C PLYITKVMSK  CCCCCCCCCC C CCCCCEEEEC  2.52% 37478858
5 439 LEYNIFEGME C RGSPLVVISQ  CCCCCCCCCC C CCCCCEEEEC  4.42% 37478858
6 504 VPRGLYDGPV C EVSVTPKTVT  CCCCCCCCCC C CCCCCEEEEC  4.87% 19483679
37478858