Protein Name:
Ubiquitin-conjugating enzyme E2 variant 2
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UniprotKB/SwissProt ID: Q15819 (Q15819)
Gene Name:
UBE2V2
Organism: Homo sapiens (Human)
Function: Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization:
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Graphical Visualization of S-nitrosylation Sites:
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| InterPro ID |
Domain Name |
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IPR000608
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UBQ-conjugat_E2_core |
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IPR016135
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UBQ-conjugating_enzyme/RWD |
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The S-nitrosylation sites of Q15819
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
69 |
ENRIYSLKVE C GPKYPEAPPS |
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