Protein Name:
Disks large homolog 2
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UniprotKB/SwissProt ID: Q15700 (Q15700)
Gene Name:
DLG2
Organism: Homo sapiens (Human)
Function: Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane. Postsynaptic density. Synapse. Membrane. Cell projection, axon. Perikaryon
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Graphical Visualization of S-nitrosylation Sites:
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