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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Thyroid receptor-interacting protein 6

UniprotKB/SwissProt ID: Q15654 (Q15654)

Gene Name: TRIP6

Organism: Homo sapiens (Human)

Function: Relays signals from the cell surface to the nucleus to weaken adherens junction and promote actin cytoskeleton reorganization and cell invasiveness. Involved in lysophosphatidic acid-induced cell adhesion and migration. Acts as a transcriptional coactivator for NF-kappa-B and JUN, and mediates the transrepression of these transcription factors induced by glucocorticoid receptor

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Nucleus. Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001781 Znf_LIM

The S-nitrosylation sites of Q15654

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 331 AVERRAYCEG C YVATLEKCAT   
2 342 YVATLEKCAT C SQPILDRILR   
3 387 FTVDATSQIH C IEDFHRKFAP   
4 402 HRKFAPRCSV C GGAIMPEPGQ   
5 47 ALQPHPRVNF C PLPSEQCYQA   
6 476 QELSATVTTD C ----------   
7 54 VNFCPLPSEQ C YQAPGGPEDR