Protein Name:
Thyroid receptor-interacting protein 11
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UniprotKB/SwissProt ID: Q15643 (Q15643)
Gene Name:
TRIP11
Organism: Homo sapiens (Human)
Function: Is a membrane tether required for vesicle tethering to Golgi. Has an essential role in the maintenance of Golgi structure and function (PubMed:25473115, PubMed:30728324). It is required for efficient anterograde and retrograde trafficking in the early secretory pathway, functioning at both the ER-to-Golgi intermediate compartment (ERGIC) and Golgi complex (PubMed:25717001). Binds the ligand binding domain of the thyroid receptor (THRB) in the presence of triiodothyronine and enhances THRB-modulated transcription
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Golgi apparatus, cis-Golgi network membrane. Cytoplasm, cytoskeleton. Endoplasmic reticulum-Golgi intermediate compartment membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q15643
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
1329 |
ASLLTPQSAE C LRASKSEVLS |
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