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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Splicing factor 1

UniprotKB/SwissProt ID: Q15637 (Q15637)

Gene Name: SF1

Organism: Homo sapiens (Human)

Function: Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR045071 BBP-like
IPR055256 KH_1_KHDC4/BBP-like
IPR004087 KH_dom
IPR036612 KH_dom_type_1_sf
IPR032570 SF1-HH
IPR047086 SF1-HH_sf
IPR001878 Znf_CCHC

The S-nitrosylation sites of Q15637

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 171 GNTLKNIEKE C NAKIMIRGKG   
2 279 ETRSITNTTV C TKCGGAGHIA   
3 282 SITNTTVCTK C GGAGHIASDC   
4 292 CGGAGHIASD C KFQRPGDPQS