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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Pumilio homolog 3

UniprotKB/SwissProt ID: Q15397 (Q15397)

Gene Name: PUM3

Organism: Homo sapiens (Human)

Function: Inhibits the poly(ADP-ribosyl)ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress (PubMed:21266351). Binds to double-stranded RNA or DNA without sequence specificity (PubMed:25512524). Involved in development of the eye and of primordial germ cells (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus, nucleolus. Nucleus, nucleoplasm. Chromosome

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR012959 CPL_dom
IPR033133 PUM-HD
IPR040059 PUM3
IPR001313 Pumilio_RNA-bd_rpt

The S-nitrosylation sites of Q15397

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 185 FAHDSTRVIQ C YIQYGNEEQR   
2 610 AIILSSLLQS C DLEVANKVKA