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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Lethal(2) giant larvae protein homolog 1

UniprotKB/SwissProt ID: Q15334 (Q15334)

Gene Name: LLGL1

Organism: Homo sapiens (Human)

Function: Cortical cytoskeleton protein found in a complex involved in maintaining cell polarity and epithelial integrity. Involved in the regulation of mitotic spindle orientation, proliferation, differentiation and tissue organization of neuroepithelial cells. Involved in axonogenesis through RAB10 activation thereby regulating vesicular membrane trafficking toward the axonal plasma membrane

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Early endosome membrane. Golgi apparatus, trans-Golgi network membrane. Golgi apparatus membrane. Cell projection, axon. Cytoplasm, cytoskeleton

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR000664 Lethal2_giant
IPR013577 LLGL2
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR036322 WD40_repeat_dom_sf
IPR001680 WD40_rpt

The S-nitrosylation sites of Q15334

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 1059 RNLAEDEAHA C AILIK-----   
2 483 LSTAGLFQTD C EHADSLAQAA   
3 636 YQRKSPVLAR C TLHPNDSLAM    37478858
4 697 EANAQLAEQA C PHDVEMTPVQ   
5 725 ADDSLSGVVR C LYFADTFLRD   
6 947 LSARNITEPL C SLDINWPRDA