Protein Name:
Rab GTPase-binding effector protein 1
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UniprotKB/SwissProt ID: Q15276 (Q15276)
Gene Name:
RABEP1
Organism: Homo sapiens (Human)
Function: Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Involved in KCNH1 channels trafficking to and from the cell membrane (PubMed:22841712). Stimulates RABGEF1 mediated nucleotide exchange on RAB5A. Mediates the traffic of PKD1:PKD2 complex from the endoplasmic reticulum through the Golgi to the cilium (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Early endosome. Recycling endosome. Cytoplasmic vesicle
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q15276
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
263 |
EKLRKELHEV C HLLEQERQQH |
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| 2 |
350 |
VEEEIKIPVV C ALTQEESSAQ |
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| 3 |
718 |
FLKEQIQAEQ C LKENLEETLQ |
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| 4 |
734 |
EETLQLEIEN C KEEIASISSL |
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