Protein Name:
Major vault protein
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UniprotKB/SwissProt ID: Q14764 (Q14764)
Gene Name:
MVP
Organism: Homo sapiens (Human)
Function: Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates IFNG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Nucleus, nuclear pore complex. Cytoplasm, perinuclear region
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q14764
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
572 |
FSVPDFVGDA C KAIASRVRGA |
CCCCEEEEEC C CCEEEEEEEC |
3.49% |
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| 2 |
59 |
RMVTVPPRHY C TVANPVSRDA |
CCCCEEEEEC C CCEEEEEEEC |
1.7% |
2212679
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