Protein Name:
Neutral alpha-glucosidase AB
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UniprotKB/SwissProt ID: Q14697 (Q14697)
Gene Name:
GANAB
Organism: Homo sapiens (Human)
Function: Catalytic subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins (PubMed:10929008). Required for PKD1/Polycystin-1 and PKD2/Polycystin-2 maturation and localization to the cell surface and cilia (PubMed:27259053)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endoplasmic reticulum. Golgi apparatus. Melanosome
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q14697
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
41 |
LAVDRSNFKT C EESSFCKRQR |
CHHHHHHHHH H HHHHHHHHHH |
5.87% |
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| 2 |
423 |
DQGFDDHNLP C DVIWLDIEHA |
CHHHHHHHHH H HHHHHHHHHH |
8.01% |
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| 3 |
47 |
NFKTCEESSF C KRQRSIRPGL |
CHHHHHHHHH H HHHHHHHHHH |
3.71% |
2212679
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| 4 |
502 |
TRDGSDYEGW C WPGSAGYPDF |
CHHHHHHHHH H HHHHHHHHHH |
4.64% |
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