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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Ribosome biogenesis protein BMS1 homolog

UniprotKB/SwissProt ID: Q14692 (Q14692)

Gene Name: BMS1

Organism: Homo sapiens (Human)

Function: GTPase required for the synthesis of 40S ribosomal subunits and for processing of pre-ribosomal RNA (pre-rRNA) at sites A0, A1, and A2. Controls access of pre-rRNA intermediates to RCL1 during ribosome biogenesis by binding RCL1 in a GTP-dependent manner, and delivering it to pre-ribosomes. GTP-binding and/or GTP hydrolysis may induce conformational rearrangements within the BMS1-RCL1 complex allowing the interaction of RCL1 with its RNA substrate. Required for RCL1 import into the nucleus

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus, nucleolus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR012948 AARP2CN
IPR039761 Bms1/Tsr1
IPR037875 Bms1_N
IPR007034 BMS1_TSR1_C
IPR030387 G_Bms1/Tsr1_dom
IPR027417 P-loop_NTPase

The S-nitrosylation sites of Q14692

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 317 VSDISFLPDP C ALPEQQKKRC   
2 556 GSKAGLSPAN C QSDRVNLEKS