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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Protein RRP5 homolog

UniprotKB/SwissProt ID: Q14690 (Q14690)

Gene Name: PDCD11

Organism: Homo sapiens (Human)

Function: Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor. Directly interacts with U3 snoRNA Involved in the biogenesis of rRNA

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus, nucleolus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR003107 HAT
IPR012340 NA-bd_OB-fold
IPR045209 Rrp5
IPR048058 Rrp5_S1_rpt_hs11_sc8
IPR048059 Rrp5_S1_rpt_hs1_sc1
IPR003029 S1_domain
IPR008847 Suf
IPR011990 TPR-like_helical_dom_sf

The S-nitrosylation sites of Q14690

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 1154 KQYQAGQTVT C FLKKYNVVKK  CCCHHHHCCC C CCCCCCCCHH  3.06%
2 1283 EDFVPQKVVR C YILSTADNVL  CCCHHHHCCC C CCCCCCCCHH  1.35%
3 1754 SHRVLQRALE C LPSKEHVDVI  CCCHHHHCCC C CCCCCCCCHH  7.62%
4 241 AKLKVGQYLN C IVEKVKGNGG  CCCHHHHCCC C CCCCCCCCHH  3.21%
5 361 QPGRPLTRLS C QNLGAVLDDV  CCCHHHHCCC C CCCCCCCCHH  3.53%
6 510 GDEVKCRVLL C DPEAKKLMMT  CCCHHHHCCC C CCCCCCCCHH  7.78%
7 535 LIESKLPVIT C YADAKPGLQT  CCCHHHHCCC C CCCCCCCCHH  1.49%
8 599 GQVVKVVVLN C EPSKERMLLS  CCCHHHHCCC C CCCCCCCCHH  7.71%
9 694 QAGDILHRVL C LSQSEGRVLL  CCCHHHHCCC C CCCCCCCCHH  2.92%
10 89 SLCEGMRILG C VKEVNELELV  CCCHHHHCCC C CCCCCCCCHH  3.37% 19483679