Protein Name:
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2
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UniprotKB/SwissProt ID: Q14571 (Q14571)
Gene Name:
ITPR2
Organism: Homo sapiens (Human)
Function: Inositol 1,4,5-trisphosphate-gated calcium channel that upon inositol 1,4,5-trisphosphate binding transports calcium from the endoplasmic reticulum lumen to cytoplasm. Exists in two states; a long-lived closed state where the channel is essentially 'parked' with only very rare visits to an open state and that ligands facilitate the transition from the 'parked' state into a 'drive' mode represented by periods of bursting activity (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endoplasmic reticulum membrane. Cytoplasmic vesicle, secretory vesicle membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q14571
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
1893 |
REMDPEIDIM C TGPEAGNTEE |
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| 2 |
253 |
FHAEQEKFLT C DEYEKKQHIF |
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| 3 |
420 |
ERPVMLKIGT C QTKEDKEAFA |
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