Protein Name:
Filamin-C
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UniprotKB/SwissProt ID: Q14315 (Q14315)
Gene Name:
FLNC
Organism: Homo sapiens (Human)
Function: Muscle-specific filamin, which plays a central role in sarcomere assembly and organization (PubMed:34405687). Critical for normal myogenesis, it probably functions as a large actin-cross-linking protein with structural functions at the Z lines in muscle cells. May be involved in reorganizing the actin cytoskeleton in response to signaling events (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Membrane. Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q14315
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
1066 |
GVLPPDPSKV C AYGPGLKGGL |
CCCCCCCCCC C CCCCCCCCCC |
2.51% |
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| 2 |
1103 |
GGLGLTVEGP C EAKIECQDNG |
CCCCCCCCCC C CCCCCCCCCC |
13.44% |
20140087
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| 3 |
1348 |
SPFRVGVTEG C DPTRVRAFGP |
CCCCCCCCCC C CCCCCCCCCC |
4.63% |
2212679
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| 4 |
1405 |
MSCKDNKDGS C TVEYIPFTPG |
CCCCCCCCCC C CCCCCCCCCC |
6.38% |
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| 5 |
1639 |
HALPTGDASK C LVTVSIGGHG |
CCCCCCCCCC C CCCCCCCCCC |
3.24% |
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| 6 |
1653 |
VSIGGHGLGA C LGPRIQIGQE |
CCCCCCCCCC C CCCCCCCCCC |
4.24% |
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| 7 |
1991 |
IRAPSGNEEP C LLKRLPNRHI |
CCCCCCCCCC C CCCCCCCCCC |
8.65% |
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| 8 |
2679 |
MVGVHGPKTP C EEVYVKHMGN |
CCCCCCCCCC C CCCCCCCCCC |
9.36% |
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| 9 |
618 |
IEGPSQAKIE C DDKGDGSCDV |
CCCCCCCCCC C CCCCCCCCCC |
10.51% |
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| 10 |
626 |
IECDDKGDGS C DVRYWPTEPG |
CCCCCCCCCC C CCCCCCCCCC |
7.39% |
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| 11 |
682 |
AFGPGLEPTG C IVDKPAEFTI |
CCCCCCCCCC C CCCCCCCCCC |
2.78% |
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| 12 |
712 |
LKLYAQDADG C PIDIKVIPNG |
CCCCCCCCCC C CCCCCCCCCC |
2.48% |
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| 13 |
728 |
VIPNGDGTFR C SYVPTKPIKH |
CCCCCCCCCC C CCCCCCCCCC |
2.76% |
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| 14 |
805 |
GQGDVSIGIK C APGVVGPAEA |
CCCCCCCCCC C CCCCCCCCCC |
5.37% |
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