Protein Name:
Large ribosomal subunit protein mL62
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UniprotKB/SwissProt ID: Q14197 (Q14197)
Gene Name:
MRPL58
Organism: Homo sapiens (Human)
Function: Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit (PubMed:20186120, PubMed:33878294). Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation (PubMed:33878294). Involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes (PubMed:20186120, PubMed:33878294)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion
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Graphical Visualization of S-nitrosylation Sites:
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| InterPro ID |
Domain Name |
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IPR052104
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Mito_Release_Factor_mL62 |
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IPR000352
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Pep_chain_release_fac_I |
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The S-nitrosylation sites of Q14197
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
82 |
IPLDRLTISY C RSSGPGGQNV |
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