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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Nucleolar GTP-binding protein 2

UniprotKB/SwissProt ID: Q13823 (Q13823)

Gene Name: GNL2

Organism: Homo sapiens (Human)

Function: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (PubMed:32669547). May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels (PubMed:26203195)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus, nucleolus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR030378 G_CP_dom
IPR024929 GNL2_CP_dom
IPR006073 GTP-bd
IPR023179 GTP-bd_ortho_bundle_sf
IPR012971 NOG2_N_dom
IPR027417 P-loop_NTPase
IPR050755 TRAFAC_YlqF/YawG_RiboMat

The S-nitrosylation sites of Q13823

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 336 VINTLRSKKV C NVAPIAGETK   
2 362 TLMRRIFLID C PGVVYPSEDS   
3 516 IKEETEENSH C DANTEMQQIL