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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Phosphatidylinositol-3-phosphate phosphatase MTMR1

UniprotKB/SwissProt ID: Q13613 (Q13613)

Gene Name: MTMR1

Organism: Homo sapiens (Human)

Function: Lipid phosphatase that specifically dephosphorylates the D-3 position of phosphatidylinositol 3-phosphate, generating phosphatidylinositol (PubMed:11733541, PubMed:27018598). Could also dephosphorylate phosphatidylinositol 3,5-bisphosphate to produce phosphatidylinositol 5-phosphate (PubMed:27018598)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane. Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR004182 GRAM
IPR037857 MTMR1_PH-GRAM
IPR030587 MTMR1_PTP
IPR030564 Myotubularin
IPR010569 Myotubularin-like_Pase_dom
IPR011993 PH-like_dom_sf
IPR029021 Prot-tyrosine_phosphatase-like
IPR016130 Tyr_Pase_AS
IPR003595 Tyr_Pase_cat
IPR000387 Tyr_Pase_dom

The S-nitrosylation sites of Q13613

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 170 IGAQSHGDNS C GIEIVCKDMR   
2 258 ISKINSNYEF C DTYPAIIVVP