Protein Name:
Dynactin subunit 2
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UniprotKB/SwissProt ID: Q13561 (Q13561)
Gene Name:
DCTN2
Organism: Homo sapiens (Human)
Function: Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules. In the dynactin soulder domain, binds the ACTR1A filament and acts as a molecular ruler to determine the length (By similarity). Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Membrane. Cytoplasm, cytoskeleton
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q13561
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
240 |
RLTELETAVR C DQDAQNPLSA |
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| 2 |
256 |
NPLSAGLQGA C LMETVELLQA |
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