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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Disintegrin and metalloproteinase domain-containing protein 9

UniprotKB/SwissProt ID: Q13443 (Q13443)

Gene Name: ADAM9

Organism: Homo sapiens (Human)

Function: Metalloprotease that cleaves and releases a number of molecules with important roles in tumorigenesis and angiogenesis, such as TEK, KDR, EPHB4, CD40, VCAM1 and CDH5. May mediate cell-cell, cell-matrix interactions and regulate the motility of cells via interactions with integrins May act as alpha-secretase for amyloid precursor protein (APP)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane. Secreted

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR006586 ADAM_Cys-rich
IPR018358 Disintegrin_CS
IPR001762 Disintegrin_dom
IPR036436 Disintegrin_dom_sf
IPR000742 EGF-like_dom
IPR024079 MetalloPept_cat_dom_sf
IPR001590 Peptidase_M12B
IPR002870 Peptidase_M12B_N
IPR034027 Reprolysin_adamalysin