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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Origin recognition complex subunit 1

UniprotKB/SwissProt ID: Q13415 (Q13415)

Gene Name: ORC1

Organism: Homo sapiens (Human)

Function: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR003593 AAA+_ATPase
IPR041083 AAA_lid_10
IPR003959 ATPase_AAA_core
IPR001025 BAH_dom
IPR043151 BAH_sf
IPR015163 Cdc6_C
IPR050311 ORC1/CDC6
IPR027417 P-loop_NTPase

The S-nitrosylation sites of Q13415

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 253 GNPQMSQQTS C ASLDSPGRIK