Protein Name:
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform
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UniprotKB/SwissProt ID: Q13362 (Q13362)
Gene Name:
PPP2R5C
Organism: Homo sapiens (Human)
Function: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and might also direct the localization of the catalytic enzyme to a particular subcellular compartment. The PP2A-PPP2R5C holoenzyme may specifically dephosphorylate and activate TP53 and play a role in DNA damage-induced inhibition of cell proliferation. PP2A-PPP2R5C may also regulate the ERK signaling pathway through ERK dephosphorylation
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Chromosome, centromere
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q13362
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
334 |
MEPLFRQLAK C VSSPHFQVAE |
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37478858
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| 2 |
408 |
MEMNQKLFDD C TQQFKAEKLK |
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